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What Are Genome Editing and CRISPR-Cas9? (Genetics Home Reference)

What Are Genome Editing and CRISPR-Cas9? (Genetics Home Reference)

"CRISPR-Cas9 was adapted from a naturally occurring genome editing system in bacteria. The bacteria capture snippets of DNA from invading viruses and use them to create DNA segments known as CRISPR arrays. The CRISPR arrays allow the bacteria to "remember" the viruses (or closely related ones). If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays to target the viruses' DNA. The bacteria then use Cas9 or a similar enzyme to cut the DNA apart, which disables the virus."

Downloadable/printable short and concise PDF with scientific journal articles for further reading from the National Library of Medicine.

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