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Cystic Fibrosis gene mutation identified

Cystic Fibrosis gene

Cystic Fibrosis gene mutation identified

Cystic fibrosis (CF), a life-threatening genetic disease that causes thick, sticky mucus to build up in the lungs, digestive tract, pancreas, and other organs, is one of the most common chronic lung diseases in children and young adults. In the early 1980s, a number of novel laboratory tools were applied to CF to try to find the gene responsible. In June 1989, researchers identified a small DNA mutation in 70% of cystic fibrosis patients, but not in healthy individuals. The discovery of the CFTR (cystic fibrosis transmembrane conductance regulator) gene is the single most important discovery to date in CF research.
1989