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Predictive Role of Succinate Dehydrogenase Mutations and Environmental Factors in Clear-Cell Renal Cell Carcinoma and Pheochromocytomas/Paragangliomas


Clear-Cell Renal Cell Carcinoma and Paragangliomas/Pheochromocytomas:Clear-Cell Renal Cell Carcinoma (ccRCC) accounts for the vast majority (85%) of all renal cancers, with around 64,000 ...
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The Effects of Genetic and Environmental Factors on Tendon Pathology: an investigation into Single Nucleotide Polymorphisms as risk factors for tendon injury


Societal Implications of Tendon Injury:Tendinopathy and tendon rupture are both very common injuries, accounting for about 1 in 2 sports injuries and 1 in 3 visits to general practitioner...
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Understanding the role of societal inequities on the risk and outcome of Acute Myeloid Leukemia


Understanding the role of societal inequities on the risk and outcome of Acute Myeloid LeukemiaWe hypothesize that racial identity and socioeconomic status are associated with the risk fo...
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Trauma’s Puzzle: Why PTSD Spares Some Amidst Universal Trauma


I: Research question: Why do only a minority of individuals exposed to traumatic events develop Post-Traumatic Stress Disorder (PTSD) despite seventy percent of the population experi...
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The Balance Of Genetic, Epigenetic, And Environmental Factors in Type 1 Diabetes


BackgroundType 1 diabetes (T1D) is a disease that plagues individuals and families worldwide, as approximately 760,000,000 people or 9.5% of the world’s population is currently afflicted ...
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Machine Learning and DNA Mutations


Missense Variants: Variations in Genes Coding for ProteinsA missense variant results from a point mutation (single nucleotide mutation) resulting in a different amino acid. There are 71 m...
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Machine Learning and Food Allergy


Abstract:How can machine learning improve food allergy diagnosis and quality of life? Food allergies represent a significant global health concern, with increasing prevalence and severe i...
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Cell-free DNA (cfDNA) as potential biomarker for disease and prenatal genetic screening.


Research on cfDNA reveals that it can be used as a biomarker, or indicator, for diseases with pathologies it directly contributes to, and its potential to be used to identify and monitor ...
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Gene editing of Lipocalin-2: potential therapeutic implications for breast cancer


Introduction An estimated 150,000 women die annually as a result of triple-negative breast cancer (TNBC).3 This figure represents about 1 out of every 3 deaths of any form of breast canc...
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CRISPR & Its Potential in Helping Blind People See


Introduction Loss of vision can be devastating for the patient and their family. Those gifted with the ability of sight might brush over just how fortunate we are in our ability to perce...
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